I am a physicist turned structural biologist working at the interface of experimental structural biology, computation, and AI. My work focuses on understanding the limits of simplified models in molecular biology and on extracting reliable insight from noisy and incomplete data.
I build and rebuild macromolecular models from cryo-EM and X-ray crystallography (MX) data, and combine this hands-on experimental expertise with AI-based structure prediction and integrative analysis (including SAXS). With 20+ structures deposited in the PDB, I also develop methods and software for the field; my programs included in CCP4 and CCP-EM form a comprehensive toolkit for macromolecular sequence validation and AI-based model rebuilding.
Formerly a staff member at EMBL Hamburg, I now work as an independent research consultant on computational and data-intensive projects, offering scientific advisory services and hands-on training to academic groups and companies.
I build and rebuild macromolecular models from cryo-EM and X-ray crystallography (MX) data, and combine this hands-on experimental expertise with AI-based structure prediction and integrative analysis (including SAXS). With 20+ structures deposited in the PDB, I also develop methods and software for the field; my programs included in CCP4 and CCP-EM form a comprehensive toolkit for macromolecular sequence validation and AI-based model rebuilding.
Formerly a staff member at EMBL Hamburg, I now work as an independent research consultant on computational and data-intensive projects, offering scientific advisory services and hands-on training to academic groups and companies.